The R1 and R2 universities in North Carolina spent $4.25B on research and development in fiscal year 2023. University of North Carolina at Chapel Hill leads with $1.55B.
| US rank | University | State | Tier | R&D | |
|---|---|---|---|---|---|
| 9 | University of North Carolina at Chapel Hill Med | NC | R1 | $1.55B | |
| 11 | Duke University Med | NC | R1 | $1.51B | |
| 53 | North Carolina State University at Raleigh Med | NC | R1 | $633M | |
| 102 | Wake Forest University Med | NC | R2 | $309M | |
| 176 | University of North Carolina at Charlotte | NC | R1 | $92M | |
| 196 | East Carolina University Med | NC | R1 | $67M | |
| 200 | North Carolina A & T State University | NC | R2 | $62M | |
| 269 | University of North Carolina Wilmington | NC | R2 | $22M | |
| 310 | Appalachian State University | NC | R2 | $8M |