The R1 and R2 universities in Pennsylvania spent $5.89B on research and development in fiscal year 2023. University of Pennsylvania leads with $1.95B.
| US rank | University | State | Tier | R&D | |
|---|---|---|---|---|---|
| 3 | University of Pennsylvania Med | PA | R1 | $1.95B | |
| 16 | University of Pittsburgh-Pittsburgh Campus Med | PA | R1 | $1.40B | |
| 23 | Pennsylvania State University-Main Campus Med | PA | R1 | $1.21B | |
| 67 | Carnegie Mellon University | PA | R1 | $485M | |
| 105 | Temple University Med | PA | R1 | $292M | |
| 112 | Thomas Jefferson University Med | PA | R2 | $258M | |
| 144 | Drexel University Med | PA | R1 | $170M | |
| 210 | Lehigh University | PA | R1 | $56M | |
| 245 | Villanova University | PA | R2 | $32M | |
| 282 | Duquesne University | PA | R2 | $15M | |
| 308 | Saint Joseph's University - Philadelphia | PA | R2 | $9M | |
| 323 | West Chester University of Pennsylvania | PA | R2 | $6M | |
| 325 | Indiana University of Pennsylvania | PA | R2 | $6M |